This most up-to-date contribution to the FAAM sequence presents a entire and recent dialogue of anaesthetic administration in being pregnant, in the course of supply, and in sufferers present process gynaecological surgical procedure. With authoritative contributions from foreign specialists it's a functional reference for all anaesthetists and professional clinicians.

Chapter 1 Maternal alterations in being pregnant (pages 1–29): James Eldrtdge
Chapter 2 the consequences of Anaesthesia and Analgesia at the child (pages 30–78): Jackie Porter
Chapter three discomfort reduction in Labour: Non?Regional (pages 79–108): Mark Scrutton
Chapter four nearby Analgesia and Anaesthesia (pages 109–177): Michael Paech
Chapter five basic Anaesthesia for Obstetrics (pages 178–200): Richard Vanner
Chapter 6 The Parturient with Co?Existing illness (pages 201–238): Philippa Groves and Michael Avidan
Chapter 7 clinical Emergencies in being pregnant (pages 239–280): Caroline Grange
Chapter eight Postnatal evaluation (pages 281–302): Robin Russell
Chapter nine Anaesthesia for Gynaecological surgical procedure (pages 303–345): Kym Osborn and Scott Simmons

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Gastro-oesophageal reflux and regurgitation during general anaesthesia for termination of pregnancy. I n t J Obsret Anesth 1992;l: 123-8. 33 Attia RR, Ebeid A, Fischer JE, Goudsouzian NG. Maternal, fetal and placental gastrin concentrations. Anaesthesia 1982;37: 18-2 1. 34 O’Sullivan G . The stomach - fact and fantasy: eating and drinking during labor. Int Anesthesiol Clin 1994;32:31-44. 35 Nimmo WS, Wilson J, Prescott LF. Narcotic analgesics and delayed gastric emptying during labour. Lancet 1975;i:890-3.

Thus unlike the mother, the baby never experiences the full extent of drug effect. However, with repeated doses or infusions, fetal tissue concentrations of many drugs approximate to maternal plasma concentrations and any drug effects are similar to those in the mother. Furthermore, accumulation of the drug in the mother and baby occurs if the interval between doses is less than the elimination half-life (T,,2p)of the drug, as is the case with most analgesic drugs. Neonatal drug elimination After birth the baby has to metabolise and/or excrete the drug.

41 Hytten FE, Paintin DB. Increase in plasma volume during normal pregnancy. J Obstet Gynaecol Br Commonwealth 1963;70:402-7. 42 Taylor DJ, Lind T. Red cell mass during and after normal pregnancy. BrJ Obster Gynaecol 1979;86:364-70. 43 Longo LD. Maternal blood volume and cardiac output during pregnancy. A m 3 Physiol 1983;245:R720-R729. 44 Lund CJ, Donovan JC. Blood volume during pregnancy: significance of plasma and red cell volumes. A m J Obstet Gynecol 1967;98:393-403. 45 Cotes PM, Canning CE, Lind T .

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